Loading an ISI file with this menu option is a shortcut for loading an ISI file, and then running Remove ISI Duplicate Records on the resulting ISI file.

Pros & Cons

Allows you to skip a common step when loading ISI files; but don't use it if you don't want to remove duplicate records from your ISI file. (In this context, a duplicate ISI record is an ISI record whose ISI unique ID has already appeared once in a given file).